A small molecule with a big target — and a fresh angle on metabolic-research questions.
5-Amino-1MQ is the odd one out in this library — it’s not a peptide either, but a small molecule — and it’s here because it tackles a metabolic question from a genuinely different direction.
What it is
It’s a research compound that acts as an NNMT inhibitor. NNMT (nicotinamide N-methyltransferase) is an enzyme that’s especially active in fat tissue, and 5-Amino-1MQ is studied for what happens when you turn its activity down.
Why that’s interesting
NNMT sits at a crossroads of metabolism. It influences NAD+ availability (the same coenzyme above) and the metabolic behaviour of fat cells. The research hypothesis is that inhibiting NNMT could shift how adipocytes — fat cells — store and burn energy, which is why most of the published interest sits in the metabolic and body-composition space.
Where the incretin peptides work on gut-hormone signalling, 5-Amino-1MQ comes at metabolism from inside the fat cell itself — a different lever entirely.
Where it sits
It’s a metabolic-research compound, conceptually adjacent to the incretin peptides like Tirzepatide and Retatrutide but with an unrelated mechanism — which is exactly what makes it useful as a comparison tool.
Handling in the lab
Supplied as a lyophilised research compound, reconstituted with bacteriostatic water and kept cold. ≥99% HPLC purity, Janoshik verified — certificate on the product page.
In the catalogue
5-Amino-1MQ
Stocked in our UK warehouse at ≥99% HPLC purity, Janoshik independently tested.
