A peptide written into your mitochondrial DNA — and one of the most intriguing compounds in exercise and metabolism research.
Most peptides are encoded by genes in the cell nucleus. MOTS-c is different, and that difference is the reason it’s become one of the most talked-about compounds in metabolic research.
What it is
MOTS-c is a mitochondrial-derived peptide — it’s encoded not in the nucleus but inside the DNA of the mitochondria, the tiny power plants inside your cells. That alone made it a discovery worth paying attention to, because it suggested mitochondria send out signalling molecules of their own, effectively talking to the rest of the body.
What the research looks at
The dominant theme is metabolism. MOTS-c has been studied for its influence on how cells use glucose and energy, with particular interest in insulin sensitivity and the AMPK pathway — a kind of master switch for cellular energy. Because that same pathway is activated by physical activity, MOTS-c is sometimes described in the research as an “exercise-mimetic” candidate.
A peptide that appears to engage the same energy machinery as exercise is, unsurprisingly, of huge interest to metabolic and ageing researchers.
Why it stands apart
Where most of our catalogue is about repair or the growth-hormone axis, MOTS-c sits in its own corner — cellular energy and mitochondrial signalling. It pairs conceptually with compounds like NAD+ in longevity-focused research.
Handling in the lab
Lyophilised powder, reconstituted with bacteriostatic water, kept cold. ≥99% HPLC purity, Janoshik verified — certificate on the product page.
In the catalogue
MOTS-c
Stocked in our UK warehouse at ≥99% HPLC purity, Janoshik independently tested.
